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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
49.09
Human Site:
S197
Identified Species:
67.5
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S197
A
S
Q
A
D
D
R
S
L
K
V
W
R
T
L
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S197
A
S
Q
A
D
D
R
S
L
K
V
W
R
T
L
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
S317
A
S
Q
A
D
D
R
S
L
K
V
W
R
T
L
Dog
Lupus familis
XP_543550
1017
111618
S197
A
S
Q
A
D
D
R
S
L
K
V
W
R
T
L
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S197
A
S
Q
A
D
D
R
S
L
K
V
W
R
T
L
Rat
Rattus norvegicus
NP_001129232
1015
111665
S197
A
S
Q
A
D
D
R
S
L
K
V
W
R
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S197
A
S
Q
A
D
D
R
S
L
K
V
W
R
T
M
Frog
Xenopus laevis
Q8QFR2
1013
112021
S197
A
S
Q
A
D
D
H
S
I
K
V
W
R
T
M
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
S197
A
S
Q
A
D
D
H
S
L
K
V
W
R
T
M
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
S197
A
S
Q
A
D
D
H
S
L
R
V
W
R
T
V
Fruit Fly
Dros. melanogaster
O17468
1047
113397
S195
A
S
Q
S
D
D
R
S
I
K
I
W
N
T
M
Honey Bee
Apis mellifera
XP_001122939
838
91355
E46
R
V
V
I
W
N
M
E
P
V
V
N
E
I
A
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
P143
V
L
T
V
E
W
S
P
N
G
K
Y
L
A
S
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
G172
G
H
T
S
L
V
K
G
V
T
W
D
P
I
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
T183
A
S
Q
S
D
D
K
T
V
I
I
W
R
T
S
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
S48
I
R
I
W
S
I
D
S
I
L
R
C
M
E
L
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
I197
T
A
S
D
D
R
T
I
K
I
F
R
Y
T
A
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
93.3
80
86.6
80
66.6
6.6
0
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
93.3
93.3
13.3
13.3
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
0
N.A.
53.3
13.3
13.3
P-Site Similarity:
N.A.
20
N.A.
86.6
20
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
71
6
0
59
0
0
0
0
0
0
0
0
0
6
12
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% C
% Asp:
0
0
0
6
77
71
6
0
0
0
0
6
0
0
0
% D
% Glu:
0
0
0
0
6
0
0
6
0
0
0
0
6
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
6
0
0
0
0
0
0
6
0
6
0
0
0
0
6
% G
% His:
0
6
0
0
0
0
18
0
0
0
0
0
0
0
0
% H
% Ile:
6
0
6
6
0
6
0
6
18
12
12
0
0
12
0
% I
% Lys:
0
0
0
0
0
0
12
0
6
59
6
0
0
0
0
% K
% Leu:
0
6
0
0
6
0
0
0
53
6
0
0
6
0
42
% L
% Met:
0
0
0
0
0
0
6
0
0
0
0
0
6
0
24
% M
% Asn:
0
0
0
0
0
6
0
0
6
0
0
6
6
0
0
% N
% Pro:
0
0
0
0
0
0
0
6
6
0
0
0
6
0
0
% P
% Gln:
0
0
71
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
6
6
0
0
0
6
48
0
0
6
6
6
65
0
0
% R
% Ser:
0
71
6
18
6
0
6
71
0
0
0
0
0
0
12
% S
% Thr:
6
0
12
0
0
0
6
6
0
6
0
0
0
77
0
% T
% Val:
6
6
6
6
0
6
0
0
12
6
65
0
0
0
6
% V
% Trp:
0
0
0
6
6
6
0
0
0
0
6
71
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
6
6
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _